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The Icatibant Outcome Survey (IOS) is an observational study monitoring safety and effectiveness of icatibant in the real‐world setting. We analyzed safety data from 3025 icatibant‐treated attacks in 557 patients (enrolled between July 2009 and February 2015). Icatibant was generally well tolerated. Excluding off‐label use and pregnancy, 438 patients (78.6%) did not report adverse events (AEs). The...
Background
Schnitzler syndrome is characterized by an urticarial rash, a monoclonal gammopathy, and clinical, histological, and biological signs of neutrophil‐mediated inflammation. The aim of this study was to assess the applicability and validity of the existing diagnostic criteria in real‐life patients.
Methods
This multicentric study was conducted between 2009 and 2014 in 14 hospitals in which...
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