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We measured the cerebral metabolic rate of glucose (CMRglc) by using positron emission tomography (PET) with [ 18 F]fluorodeoxyglucose (FDG) and the choline acetyltransferase (ChAT) activity at 3 days and 3 months after destruction of the nucleus basalis magnocellularis (NBM). Although the frontal ChAT activity remained 20% lower than that of controls even at 3 months post-lesioning,...
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