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Myocardial ischemia followed by reperfusion is associated with injury and myocardial stunning. Circulating cytokines may play a role in reperfusion injury. Methods: We examined effect of serum from dogs undergoing LAD occlusion and reperfusion on contractility of beating myocytes. Anaesthetized dogs (n = 3) were subjected to 3 hours of LAD occlusion and 3 hours of reperfusion. Control dogs (n =...
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