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2,2'-Pyridylisatogen tosylate (PIT) is both an allosteric modulator of P2Y receptors, and an immine oxide, acting as a spin trap for free radicals. PIT (10 mg kg -1 , i.p.) was found to be a powerful neuroprotective agent in protecting against the lesions induced by 15 μg S-bromo-willardiine injected into the cortex or white matter of 5-day-old mice pups. As the multiple effects of PIT...
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