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An accurate and reliable UPLC–MS/MS method is reported for the quantification of endogenous Prostaglandin E2 (PGE2) in rat colonic mucosa and polyps. This method adopted the “surrogate analyte plus authentic bio-matrix” approach, using two different stable isotopic labeled analogs — PGE2-d9 as the surrogate analyte and PGE2-d4 as the internal standard. A quantitative standard curve was constructed...
This paper proposes one kind of MD5-based error-detecting mechanism. The 128-bit MD5 code is compressed into 16-bit error-detecting code in order to substitute for that computed with CRC or checksum. In this mechanism, computer-simulating technology is used to simulate natural and manual attacks. The evaluation method is to corrupt the data of each packet which is produced by a random number generator...
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