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Glycoalkaloids are naturally occurring toxins in potatoes, which at high levels may induce toxic effects in humans, mainly on the gastrointestinal tract by cell membrane disruption. In order to better understand the molecular mechanisms underlying glycoalkaloid toxicity, we examined the effects of α-chaconine on gene expression in the Caco-2 intestinal epithelial cell line using DNA microarrays. Caco-2...
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