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Annexin A5 (Anx) has been extensively used for imaging apoptosis by single‐photon emission computed tomography, positron emission tomography, optical imaging and MRI. Recently we introduced ultrasmall Anx–VSOP (very small iron oxide particles) – the smallest high‐relaxivity probe for MRI of apoptosis. Here we present a simplified method for the direct coupling of Anx to VSOP, which resulted in nanoparticles...
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