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Dietherification of the hydroxy groups of various α,α-disubstituted α-amino acids or their precursors, possessing either an achiral frame derived from α-hydroxymethylserine, or a 2,2',6,6'-tetrasubstituted biphenyl frame with only an axial chirality, or a frame with α-carbon chirality derived from α-methyl-(L)-DOPA, using (R)-2,2'-bis-(5-tosyloxy-3-oxa-1-pentyloxy)-1,1'-binaphthyl as alkylating agent,...
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