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A novel cell‐targeting, near‐infrared light‐responsive drug delivery platform based on mesoporous silica‐coated gold nanorods that are surface‐functionalized with aptamer DNA is constructed. Aptamer DNA is used as both capping and targeting agent. In vitro studies show the feasibility of using this nanocarrier for targeted and noninvasive remote controlled drug delivery and photothermal therapy.
Multifunctional drug‐delivery systems have shown promising applications in cancer therapy. J. Ren, X. Qu, and co‐workers report a novel, cell‐targeting, NIR light responsive drug‐delivery system on page 2890, which is based on gold nanorods incorporated within a mesoporous silica framework and surface‐functionalized with aptamer DNA. With its high NIR absorbance, good biocompatibility, and selectivity,...
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