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The influence of loading indomethacin (IMC) on the thermosensitive aggregation of a double hydrophilic graft copolymer dextran-graft-poly(N-isopropylacrylamide) (DgP) was studied. Before IMC-loading, DgP forms loose aggregates of unimers in aqueous solution below the lower critical solution temperature (LCST), while compact nanoparticles appear above the LCST because of the phase transition of the...
Porous coordination nanocages covered with alkyne groups are synthesized through judicious selection of the ligand and reaction conditions. The surface functionalization via click reaction with azide‐terminated polyethylene glycol turns them into water‐stable colloids, which exhibit controlled release of an anticancer drug 5‐fluorouracil.
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