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Back Cover: Micelles prepared by self‐assembly of an amphiphilic furoxan‐bearing block copolymer release nitric oxide in response to cysteine and potentiate the anti‐proliferative effect of ibuprofen in human colon cancer cells. Further details can be found in the article by U. Hasegawa, T. J. Wang, J. Y. Chen, H. Uyama, and A. J. van der Vlies on page 1009.
Furoxans, or 1,2,5‐oxadiazole‐N‐oxides, are a class of nitric oxide (NO)‐donating compounds that release NO in response to thiol‐containing molecules. In this study, polymeric micelles bearing furoxan moieties are prepared from an amphiphilic block copolymer consisting of a hydrophobic furoxan‐bearing block and a hydrophilic poly(N‐acryloylmorpholine) block. The block copolymer is prepared using a...
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