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Cells can perceive complex mechanical cues across both the micro‐ and nanoscale which can influence their development. While causative effects between surface topography and cellular function can be demonstrated, the variability in materials used in this screening process makes it difficult to discern whether the observed phenotypic changes are indeed a result of topographical cues alone or the inherent...
High‐Throughput Screening
In article number 2100881, Nicolas H. Voelcker, Jessica E. Frith, Victor J. Cadarso, and co‐workers demonstrate a novel approach to imprint micro and nanoscaled topographical features into conventional cell cultureware, facilitating its compatibility with standard biological techniques. This enables high‐throughput screening to integrate the effects of surface topographies...
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