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Microglia are Central Nervous System (CNS) cells that are similar to macrophages. They undergo characteristic changes in cell arbor morphology in response to tissue perturbation. Ensembles of microglia exhibit a progression of arbor morphologies. Our goal is to discover these progressions and determine the underlying arbor features from 3-D multi-channel fluorescence confocal microscope images of...
Microglia are the resident immune cell population in the mammalian central nervous system (CNS). These highly plastic cells exhibit ramified arbors in their resting state, and progressively less-complex arbors when activated. Our goal is to compare the spatial distributions of resting and activated microglia in normal brain tissue against tissue that is perturbed by insertion of a neural recording...
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