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This works presents the development of a detoxification system based on bacterial phosphotriesterase (PTE) for the degradation of organophosphate (OP) insecticides in water. PTE was immobilised on an activated agarose gel via covalent coupling. Two different OPs were studied, chlorpyrifos and chlorfenvinfos, due to their importance in the field of water policy. The efficiency of insecticide degradation...
This work shows the possibility of combining the high sensitivity of genetically-modified Drosophila melanogaster acetylcholinesterase (B394) with the ability of phosphotriesterase (PTE) to hydrolyse organophosphate compounds, in the aim of developing a biosensor selective to two insecticides of interest: chlorpyrifos and chlorfenvinfos. The studies clearly demonstrate that chlorfenvinfos is a substrate...
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