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It is shown that the partition behavior of solutes in a given aqueous two-phase systems can be manipulated using a nonionic additive, the trimethylamine N-oxide (TMAO). To this end, partitioning of a set of proteins and small organic compounds was analyzed in aqueous Dextran-75-Polyethylene glycol (PEG-600)-0.15 M sodium sulfate-0.01 M sodium/potassium phosphate buffer, pH 7.4 two-phase systems with...
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