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We have tested the gene encoding cortexin, Ctxn, which maps to chromosome 8, as a candidate for the mouse neurological mutants: nervous (nr), tottering (tg) plus tottering-leaner (tg la ), and motor neuron degeneration (mnd) by Northern blot analysis of brain poly(A) + RNA and direct polymerase chain reaction (PCR) sequencing. No difference from wild-type was seen in any of these...
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