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The effect of poly(ethylene glycol)-phospholipid (PE-PEG) lipopolymers on phospholipase A 2 (PLA 2 ) hydrolysis of liposomes composed of stearoyl-oleoylphosphatidylcholine (SOPC) was investigated. The PLA 2 lag-time, which is inversely related to the enzymatic activity, was determined by fluorescence, and the zeta-potentials of the liposomes were measured as a function of PE-PEG...
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