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Objective
IgG4‐related sialadenitis (IgG4‐RS) is a chronic fibroinflammatory disease characterized by glandular fibrosis and hyposalivation. This study was undertaken to explore the role of cellular senescence in the pathogenesis of IgG4‐RS–related fibrosis.
Methods
The expression of senescence markers and proinflammatory cytokines in the submandibular glands (SMGs) of IgG4‐RS patients (n = 18)...
Objective
Systemic lupus erythematosus (SLE) is a prototypical autoimmune disease with differences in prevalence and severity among ancestral groups. This study was undertaken to identify novel genetic components, either shared by or distinct between Asian and European populations.
Methods
Both trans‐ancestral and ancestry‐specific meta‐analyses of genome‐wide association studies (GWAS) for SLE...