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Asthma is a major public health burden worldwide. Studies from our group and others have demonstrated that SERPINB3 and SERPINB4 are induced in patients with asthma; however, their mechanistic role in asthma has yet to be determined.To evaluate the role of Serpin3a, the murine homolog of SERPINB3 and SERPINB4, in asthma.We studied wild-type Balb/c and Serpinb3a-null mice in house dust mite or IL-13–induced...
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