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The development of recombinant factor VIIa (rFVIIa) has greatly augmented the range of treatment options available for hemophilia patients with inhibitors. However, there still remains a lack of consensus regarding several aspects of treatment with bypassing agents such as rFVIIa, prothrombin complex concentrates (PCC), and activated PCC (aPCC). Such unresolved issues may be clarified by the identification...
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