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Inhibitory effects on the monophenolase activity of tyrosinase of some aryl butenes derivatives, having moderate to excellent inhibitory activity on MDA-MB-231 breast cancer cell, have been examined. The results show that the substitution of the phenol group by other functional moieties or its removal (unsubstituted phenyl) makes the loss of the tyrosinase inhibition effect of the compounds. Interestingly,...
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