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This paper reports on polymer solid microneedles with pyramid-shaped tips and titanium shields for transdermal transportation of drug molecules, bio-macromolecules, or nano-particles. Microelectromechanical system (MEMS) techniques, such as masking, etching, alignment, development, sputtering, were adapted to produce polymer microneedles with sharp tips to reduce the force to pierce into skin. Polymer...
The paper proposes a novel design concept and fabrication method of micro dispensing chip. The filling process is performed by capillary force without extra energy, greatly reducing the complexity of design and operation. The annular interspaces around the nozzles in the chip can help the droplet formation on the hydrophilic surfaces, and the step conjunction between the channel and the reservoir...
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