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Surface imprinting over nanostructured matrices is an effective solution to overcome template removal and achieve high binding capacity. In this work, a facile method was developed for synthesis of polydopamine-coated molecularly imprinted silica nanoparticles (PDA-coated MIP silica NPs) based on self-polymerization of dopamine (DA) on the surface of silica NPs in the presence of template protein...
A feasible and practicable amperometric immunoassay strategy for sensitive screening of carcinoembryonic antigen (CEA) in human serum was developed using carbon nanotube (CNT)-based symbiotic coaxial nanocables as labels. To construct such a nanocable, a thin layer of silica nanoparticles was coated on the CNT surface by sonication and sol–gel methods, and then colloidal gold nanoparticles were assembled...
Novel ratiometric fluorescent silica nanoparticles with high selectivity towards Hg 2+ were synthesized for the detection of Hg 2+ . Hg 2+ promoted the ring opening of spirolactam in the rhodamine moiety grafted onto the silica nanoparticles, resulting in a change in the fluorescence intensity. The fluorescence intensity was proportional to the Hg 2+ concentration,...
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