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P2X 7 receptor (P2X 7 R) has been shown to mediate an anticancer effect via apoptosis in different types of cancer. However, whether P2X 7 R exerts a promoting or suppressive effect on brain glioma is still a controversial issue and its underlying mechanism remains unknown. We showed here that P2X 7 R suppression exerted a pro-growth effect on glioma through directly...
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