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Early evidence has shown that HPLC columns packed with a given ODS phase give different performance, related to differences in their packing densities and external porosities. This effect was systematically studied on two groups of ten analytical (10 0.46 cm) columns packed with Kromasil and Zorbax 10 μm spherical C 18 , respectively, using chloroform as the slurry solvent and methanol...
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