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A novel polypeptide containing the unusual posttranslationally modified amino acidsl-3,4,5-trihydroxyphenylalanine (TOPA) andl-6-bromotryptophan (6-BrW) has been isolated from the morula cells of the vanadium-accumulating ascidian,Phallusia mammillata.The polypeptide, designated Morulin Pm, has a molecular weight of 3825 ± 0.6 and has a simple amino acid composition consisting mainly of TOPA and 6-BrW...
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