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Background & Aims: Necrotizing enterocolitis (NEC) is the most common gastrointestinal emergency of premature infants. While the effect of bile acids (BAs) on intestinal mucosal injury is known, we investigated the contribution of BAs during the development of NEC in neonatal rats. Methods: Premature rats were fed with cow’s milk–based formula and subjected to asphyxia and cold stress to develop...
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