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Ovine scrapie can be transmitted via environmental reservoirs. A pool of ovine scrapie isolates were incubated on soil for one day or thirteen months and eluted prion was used to challenge tg338 mice transgenic for ovine PrP. After one-day incubation on soil, two PrP Sc phenotypes were present: G 338 or Apl 338 ii. Thirteen months later some divergent PrP...
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