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ObjectivesCaspases, a family of cysteine proteases with unique substrate specificities, contribute to apoptosis, whereas autophagy‐related genes (ATGs) regulate cytoprotective autophagy or autophagic cell death in cancer. Accumulating evidence has recently revealed underlying mechanisms of apoptosis and autophagy; however, their intricate relationships still remain to be clarified. Identification...
Natural compounds derived from plant sources are well characterized as possessing a wide variety of remarkable anti‐tumour properties, for example modulating programmed cell death, primarily referring to apoptosis, and autophagy. Distinct from apoptosis, autophagy (an evolutionarily conserved, multi‐step lysosomal degradation process in which a cell destroys long‐lived proteins and damaged organelles)...
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