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Intraoperative radiotherapy (IORT) could be not-inferior to external beam radiotherapy (EBRT) in selected patients, but toxicities, self-perception of body image, quality of life, and resumption of work or daily activities have been poorly explored. The aim of the present study was to compare these outcomes between EBRT, IORT full-dose (IORT-f) and IORT boost (IORT-b).443 consecutive patients, candidates...
The rationale for the irradiation of a limited volume of tissue around the surgical bed in place of whole breast irradiation comes from numerous studies that have shown that 80% or more of local relapses after conservative surgery and radiation therapy occur at the original tumor site. Particularly in low-risk patients, a more limited local treatment could be justified. Intraoperative radiotherapy...
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