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Commensal flora plays an important role in the development of the mucosal immune system and in maintaining intestinal homeostasis. However, the mechanisms involved in regulation of host‐microbiota interaction are still not completely understood. In this study, we examined how microbiota and intestinal inflammatory conditions regulate host microRNA expression and observed lower microRNA‐107 (miR‐107)...
Regulatory T (Treg) cells are plastic, but the in vivo mechanisms by which they are converted into foxhead box p3 (Foxp3 + ) interferon (IFN)-γ + T cells and whether these converted cells retain the ability to inhibit colitis are not clear.Foxp3 + Treg cells were generated by culture of naïve CD4 + T cells from Foxp3 GFP CBir1 T-cell receptor (TCR) transgenic...
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