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AimThe aim of this study was to differentiate human embryonic stem cells (hESCs) into odontoblastic lineage in an optimized culture milieu.
MethodologyIn Phase 1, hESCs were differentiated into mesenchymal stem cells (H9‐MSCs). In Phase 2, H9‐MSCs were then differentiated into odontoblast‐like cells (H9‐Odont) under the stimulation of FGF‐8 and BMP‐4. Alternatively, H9‐MSCs were differentiated into...
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