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The importance of the adrenergic nervous system in supporting the failing heart has long been known. The adrenergic drive on cardiac structure and function has however some adverse effects, which include myocardial β -adrenoceptor (β -AR) downregulation and decreased β -adrenergic responsiveness to cathecolamines. In dog lymphocytes, β 1 -AR and β 2 -AR populations are almost equally...
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