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Introduction: Animal models used to study hyperammonaemic disorders related to chronic liver disease are unsatisfactory. These animals only develop hyperammonaemia and brain oedema when fed with diets supplemented with amonium acetate.
Aim: To develop a novel experimental model of hyperammonaemia and brain oedema in CCl4‐induced cirrhosis in rats.
Methods: Four groups were studied: rats with sham...
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