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Gould-Jacob type of reaction for the synthesis of thieno[3,2-e]pyrimido[1,2-c]pyrimidines (5) has been carried out conventionally by the condensation between 4-aminothieno[2,3-d]pyrimidines (2) and diethyl ethoxymethylenemalonate (3) via acyclic intermediates diethyl N-[5,6-disubstituted thieno[2,3-d]pyrimidin-4-yl]aminomethylenemalonates (4) and the results obtained were compared with single step...
A single step synthesis of various heterocycles such as 2-cyano-5-phenylpyrrolo[1,2-a]quinazolines (6), 5-phenyl-7-cyano-8,9,10,11-tetrahydroindolo[1,2-a]quinazoline (7), 2-cyanocyclopenta[4,5]thieno[3,2-e]pyrrolo[1,2-a]-pyrimidin-5(4H)-ones (9) and 4-(2-amino-3-cyanopyrrol-1-yl)-5-carbethoxythiazole-2-thiones (10) have been reported using 2-haloalkylidenepropanedinitriles (1) and (2) with 5-substituted...
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