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Tissue Regeneration
In article number 2300180, Hao Chen, Wenguo Cui, Yuhui Zhang, and co‐workers propose a hydrogel‐microsphere‐based synthetic niche with cell recruiting and targeted cell differentiation properties via mechanotransduction. The microsphere niche guides the fate of endogenous stem cells in the aberrant mechanical microenvironment, offering an effective strategy for enhancing the endogenous...
The aberrant mechanical microenvironment in degenerated tissues induces misdirection of cell fate, making it challenging to achieve efficient endogenous regeneration. Herein, a hydrogel microsphere‐based synthetic niche with integrated cell recruitment and targeted cell differentiation properties via mechanotransduction is constructed . Through the incorporation of microfluidics and photo‐polymerization...
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