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Objective To further explore the mechanism of etanercept (ENT, rhTNFR:Fc) and methotrexate (MTX) in the combined treatment of rheumatoid arthritis (RA), we investigated whether thymic and splenic T-cell subsets and their related cytokines imbalance could be restored by ETN/MTX treatment. Methods The effect of ETN/MTX on collagen-induced arthritis (CIA) was evaluated by arthritis scores, joint and...
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