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Recent advances in the self-assembly of biomimetic interfaces permit the development of biosensor arrays that harness the unique sensitivity and selectivity of membrane proteins. Integrating these interfaces into microsystem platforms for point-of-care and high throughput screening applications requires compact, multi-channel readout circuitry to measure interface impedance over a broad frequency...
Electrochemical impedance spectroscopy (EIS) is a powerful tool for characterizing biological materials, including lipid bilayers and many membrane proteins. However, traditional EIS methods are very slow at low frequencies, where these materials respond in biosensor applications. To enable dense arrays of biosensors based on tethered bilayer lipid membranes (tBLM), a new approach for EIS has been...
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