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The SK3 channel, a small-conductance calcium-activated potassium channel, is expressed in immature fibers of skeletal muscle and becomes down regulated after innervation. We have previously shown that the level of mRNA of the SK3 channel is increased in muscle from myotonic dystrophy. In this study, we have carried out an immunohistochemical study using a polyclonal anti-SK3 antibody. SK3 protein...
We investigated gene expression patterns of ion channels including the apamin-sensitive small-conductance Ca 2+ -activated K + (SK3) channel, the adult isoform of the skeletal muscle Na + channel (SkM1), the fetal isoform of skeletal muscle Na + channel (H1), and the Cl - channel (ClC-1) by using the semiquantitative reverse transcriptase-polymerase chain...
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