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Increased airway smooth muscle (ASM) is a feature of established asthma in schoolchildren, but nothing is known about ASM in preschool wheezers.We sought to determine endobronchial biopsy specimen ASM area fraction in preschool wheezers and its association with asthma at school age.ASM area, reticular basement membrane thickness, and mucosal eosinophil and ASM mast cell values were quantified in endobronchial...
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