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Background and Aims
To identify the regulatory role of protein phosphatase 2A (PP2A) in the development of liver disease, we generated a mouse model with hepatocyte‐specific deletion of Ppp2r1a gene (encoding PP2A Aα subunit).
Approach and Results
Homozygote (HO) mice and matched wild‐type littermates were investigated at 3, 6, 9, 12, 15, and 18 months of age. Pathological examination showed that...
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