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Although serum tau protein levels increase following TBI, the time course is unknown. The aim of the present study was to determine whether serum tau protein levels increased in both a severity-dependent and time-dependent manner in an experimental model of rat traumatic brain injury (TBI).A total of 24 Sprague-Dawley rats were subjected to varying grades of TBI using a contusion injury model on the...
The identification of reliable outcome predictors after traumatic brain injury (TBI) is crucial. The objective of our study was to investigate the role of τ protein as a serum marker of TBI.Thirty-four patients with severe TBI (Glasgow Coma Scale [GCS] score at admission ≤ 8) were considered. The τ protein level in the blood samples obtained at the time of admission was measured. The outcome was assessed...
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