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Intravascular large B‐cell lymphoma (IVLBCL) is a distinct disease, but the neoplastic PD‐L1 expression on tumor cells may vary among cases. We evaluated 10 IVLBCL autopsy cases for neoplastic PD‐L1 expression, and had positive results in two cases. In one case, neoplastic PD‐L1 expression (SP142, 28‐8, and E1J2J clones) was dependent on the organ and anatomical site (capillaries vs. vessels) of...
We identified six patients with Epstein‐Barr virus (EBV)‐negative extranodal diffuse large B‐cell lymphoma (DLBCL) and immunohistochemical expression of PD‐L1 on their tumor cells by examining 283 DLBCL cases with the PD‐L1 SP142 clone between 2015 and 2017. They consisted of two men and four women with a median age of 71 years, and were examined in an autopsy (n = 1) and biopsies from the adrenal...
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