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The cover image is based on the Research Letter Origins and mechanisms leading to aneuploidy in human eggs by Lena Wartosch et al., https://doi.org/10.1002/pd.5927.
The gain or loss of a chromosome—or aneuploidy—acts as one of the major triggers for infertility and pregnancy loss in humans. These chromosomal abnormalities affect more than 40% of eggs in women at both ends of the age spectrum, that is, young girls as well as women of advancing maternal age. Recent studies in human oocytes and embryos using genomics, cytogenetics, and in silico modeling all provide...
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