The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
Chronic diabetic wounds remain a worldwide challenge for both the clinic and research. Given the vicious circle of oxidative stress and inflammatory response as well as the impaired angiogenesis of the diabetic wound tissues, the wound healing process is disturbed and poorly responds to the current treatments. In this work, a nickel‐based metal‐organic framework (MOF, Ni‐HHTP) with excellent antioxidant...
The interface adhesion plays a key role between rigid metal and elastomer in compressible and stretchable conductors. However, the poor interfacial adhesion hinders their wide applications. To strengthen the interface adhesion, herein, a combination strategy of structure interlocking and polymer bridging is designed by introducing a method of subsurface‐initiated atom transfer radical polymerization...
Ultrasensitive Plasmonic Sensors
In article number 2303026, Lixuan Liu, Yu Shu, Tianyu Xue, and co‐workers present the ferroelectric 2D Bi2O2Se materials, which exhibit an ultralow detection limit of 1 fM for protein molecule detection using plasmonic biosensors. Notably, the unique ferroelectric property of Bi2O2Se materials enhances the signal of plasmonic biosensors. It is anticipated that the...
Plasmonic biosensing is a label‐free detection method that is commonly used to measure various biomolecular interactions. However, one of the main challenges in this approach is the ability to detect biomolecules at low concentrations with sufficient sensitivity and detection limits. Here, 2D ferroelectric materials are employed to address the issues with sensitivity in biosensor design. A plasmonic...
The main obstacles for the commercial application of Lithium–Sulfur (Li–S) full batteries are the large volume change during charging/discharging process, the shuttle effect of lithium polysulfide (LiPS), sluggish redox kinetics, and the indisciplinable dendritic Li growth. Especially the overused of metal Li leads to the low utilization of active Li, which seriously drags down the actual energy density...
Sonodynamic therapy (SDT) has attracted intensive attention, but is still hindered by low sonosensitization and non‐biodegradability of the traditional sonosensitizers. Herein, perovskite‐type manganese vanadate (MnVO3) sonosensitizers integrating high reactive oxide species (ROS) production efficiency and appropriate bio‐degradability are developed for enhanced SDT. Taking advantage of the intrinsic...
Lithium‐sulfur battery has attracted significant attention by virtues of their high theoretical energy density, natural abundance, and environmental friendliness. However, the notorious shuttle effect of polysulfides intermediates severely hinders its practical application. Herein, a novel 2D mesoporous N‐doped carbon nanosheet with confined bimetallic CoNi nanoparticles sandwiched graphene (mNC‐CoNi@rGO)...
The establishment of effective antitumor immune responses of vaccines is mainly limited by insufficient priming tumor infiltration of T cells and immunosuppressive tumor microenvironment (TME). Targeting β‐adrenergic receptor (β‐AR) signaling exerts promising benefits on reversing the suppressive effects directly on T cells, but it appears to have considerably limited antitumor performance when combined...
A series of Ru‐based catalysts have been developed for the hydrogen evolution reaction (HER) by the facile impregnation of copious and eco‐friendly bacterial cellulose (BC) with Ru(bpy)3Cl2 (bpy = 2,2′‐bipyridine) followed by pyrolysis. After the oxidation and molecular recomposition processes that occur within the BC precursors during pyrolysis, sub‐2 nm Ru nanoparticles (NPs) and atomic Ru species...
In article number 2100006, Wen Sun, Wen‐fei Dong, Dan Shao, and co‐workers fabricate diselenide‐bridged mesoporous organosilica nanoparticles for coordination and redox dual‐responsive delivery of chemotherapeutic ruthenium compound KP1339. Such immunogenic cell death nano‐amplifier performed robust suppression on primary and distant tumor growth, as well as pulmonary metastasis of breast cancer with...
Amplifying the chemotherapy‐driven immunogenic cell death (ICD) for efficient and safe cancer chemoimmunotherapy remains a challenge. Here, a potential ICD nanoamplifier containing diselenide‐bridged mesoporous organosilica nanoparticles (MONs) and chemotherapeutic ruthenium compound (KP1339) to achieve cancer chemoimmunotherapy is tailored. KP1339‐loaded MONs show controlled drug release profiles...
An in situ coupling approach is used to fabricate the porous carbon liquid with permanent porosity by directly dispersing hollow carbon nanospheres in polymerized ionic liquids. It is a kind of homogenous and stable type III porous liquid at room temperature. Because of the well‐preserved permanent porosity, this unique porous carbon liquid is capable of absorbing the largest quantity of carbon dioxide...
In article number 1800785, Guobin Wang, Shuai Wang, Zheng Wang, Lin Wang, and co‐workers fabricate a versatile nanoplatform composed of gold‐nanodot‐decorated hollow carbon nanospheres with hyaluronic acid coating (AuHCNs‐HA). Such a nanoplatform serves as a trimodal drug delivery and therapeutic system. Using this system, their work reveals that weak photothermal effects and weak photodynamic effects...
Despite the therapeutic usefulness of near‐infrared irradiation (NIR)‐induced potent photothermal effects (PTE) and photodynamic effects (PDE), they inevitably damage normal tissues, often posing threat to life when treating tumors adjacent to key organs or major blood vessels. In this study, the frequently overlooked, “weak” PTE and PDE (no killing capability) are employed to synergize chemotherapy...
Sericin‐wrapped mesoporous silica nanoparticles (SMSNs) with pH and protease dual responsiveness are successfully fabricated as a lysosome‐targeting drug delivery system by Guobin Wang, Lin Wang, Zheng Wang, and co‐workers in article number 1602567. Such a dual responsive system offers a rapid doxorubicin release in lysosomes, which bypasses the membrane pump mediated drug efflux, thereby achieving...
Multidrug resistance (MDR) and adverse side effects are the major challenges facing cancer chemotherapy. Here, pH/protease dually responsive, sericin‐coated mesoporous silica nanoparticles (SMSNs) for lysosomal delivery of doxorubicin (DOX) to overcome MDR and reduce systemic toxicity are reported. Sericin, a natural protein from silkworm cocoons, is coated onto MSNs as a gatekeeper via pH sensitive...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.