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A major challenge in stroke treatment is the restoration of neural circuit in which neuron function plays a central role. Although transplantation of exogenous neural stem cells (NSCs) is admittedly a promising therapeutical means, the treatment outcome is greatly affected due to the poor NSCs differentiation into neurons caused by myelin associated inhibitory factors binding to Nogo‐66 receptor (NgR)...
A multifunctional nanoscale polymersome is developed for directing neuronal differentiation of neural stem cells (NSCs) by Jun Shen and co‐workers in article number 1706769. Superparamagnetic iron oxide nanoparticles and small interfering RNA can be co‐delivered into NSCs, allowing for directing neuronal differentiation through silencing the NgR gene and non‐invasive migration monitoring. The study...
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