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γ‐Aminobutyric acid (GABA), as the primary inhibitory neurotransmitter, is extremely important for maintaining healthy brain function, and deviations from GABA homeostasis are related to various brain diseases. Short‐echo‐time (short‐TE) proton MR spectroscopy (1H‐MRS) has been employed to measure GABA concentration from various human brain regions at high magnetic fields. The aim of this study was...
Localized in vivo 1 H NMR spectroscopy was performed with 2-ms echo time in the rat brain at 9.4 T. Frequency domain analysis with LCModel showed that the in vivo spectra can be explained by 18 metabolite model solution spectra and a highly structured background, which was attributed to resonances with fivefold shorter in vivo T 1 than metabolites. The high spectral resolution (full...
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