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Purpose
To understand how macromolecular content varies in the human brain with age in a large cohort of healthy subjects.
Methods
In‐vivo 1H‐MR spectra were acquired using ultra‐short TE STEAM at 7T in the posterior cingulate cortex. Macromolecular content was studied in 147 datasets from a cohort ranging in age from 19 to 89 y. Three fitting approaches were used to evaluate the macromolecular...