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The objective of this study was to investigate the bioactivity and protein‐resistant properties of dual functioning surfaces modified with PEG for protein resistance and corn trypsin inhibitor (CTI) for anticoagulant effect. Surfaces on gold substrate were prepared with varying ratios of free PEG to CTI‐conjugated PEG. Two methods designated, respectively, “sequential” and “direct” were used. For...
Blood contacting surfaces bind plasma proteins and trigger coagulation by activating factor XII (FXII). The objective of this work was to develop blood contacting surfaces having the dual properties of protein resistance and inhibition of coagulation. Gold was used as a model substrate because it is amenable to facile modification using gold–thiol chemistry and to detailed surface characterization...
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