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The aim of this study was to investigate the effect of smoking on the atherosclerotic risk indicators, the independent risk factors for the plasma homocysteine, and for the mean carotid intima media thickness (mIMT) in the smoker and nonsmoker groups. A total of 213 male subjects, consisting of 96 smokers and 117 nonsmokers, were recruited. Smokers had significantly greater plasma triglyceride level...
The polymorphism of the gene encoding methylenetetrahydrofolate reductase (MTHFR) and folic acid nutritional status play important roles in atherosclerosis. The present study investigated the total homocysteine-lowering effect of folic acid in response to the MTHFR genotype in patients who have cardiovascular disease. Twenty-three patients who had cardiovascular disease (ages 44 to 88 y) were supplemented...
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